Francis or Fran O'Brien may refer to: __NOTOC__ Politics Francis O'Brien (Canadian politician) (born 1927), Canadian politician and farmer Francis O'Brien (Irish politician) (born 1943), Irish Fianna Fáil politician
Sport Francis O'Brien (cricketer) (1911–1991), New Zealand cricketer Fran O'Brien (American football) (1936–1999), American National Football League player Fran O'Brien (footballer) (born 1955), Irish footballer
Other Francis O'Brien, executive producer of Gallipoli (1981 film)
See also Frank O'Brien (disambiguation)