Santiago González may refer to:
Santiago González Bonorino (born 1975), Argentine rugby union player Santiago González (footballer, born 1992), Uruguayan football player Santiago González (footballer, born 1999), Argentine football player Santiago González (footballer, born 2003), Argentine football player Santiago González Iglesias (born 1988), Argentine rugby union player Santiago González Larraín (born 1956), Chilean engineer and government minister Santiago González Portillo (1818–1887), president of El Salvador in 1871–1876 Santiago González Soto (born 1961), Mexican journalist and politician Santiago González (tennis) (born 1983), Mexican tennis player
See also Luz M. Santiago González (born 1957), Puerto Rican politician