Niederhoffer is a surname of German origin and may refer to the following people:
Arthur Niederhoffer (1917–1981), American sociologist and police officer Galt Niederhoffer (born 1976), American movie producer and novelist Roy Niederhoffer (born 1966), American hedge fund manager and philanthropist Victor Niederhoffer (1943– 2026), American hedge fund manager, U.S. Squash Champion and Paddleball Champion, bestselling author, and statistician.