M105 or M-105 may refer to:
Messier 105, an elliptical galaxy in the constellation Leo M105, a 1½ ton US Army trailer M-105 (Michigan highway), a former state highway in Michigan Klimov M-105 aircraft engine CFXM-FM, a radio station in Granby, Quebec, branded M105 WWWM, a radio station in Cleveland, Ohio now known as WMJI
In athletics: Masters athletics, an age group for athletes aged 35+
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