Ptychochromis makira is a species of cichlid only known from the Antainambalana River in the northernmost part of the Toamasina Province in Madagascar.Stiassny, M., and Sparks, J. S. (2006). Phylogeny and Taxonomic Revision of the Endemic Malagasy Genus Ptychochromis (Teleostei: Cichlidae), with the Description of Five New Species and a Diagnosis for Katria, New Genus. American Museum Novitates 3535. It is threatened by habitat loss and overfishing, and has suffered a severe decline in recent years. It reaches a length of SL.

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