Memorial Square is a neighborhood located in Springfield, Massachusetts.

A predominantly Puerto Rican neighborhood with several parks, Memorial Square is within walking distance of Springfield's three nationally ranked hospitals, Baystate Medical Center, Shriner's Children's Hospital, and Mercy Medical.

Always a neighborhood of immigrants, Memorial Square was a primarily Greek neighborhood from the Industrial Revolution until the 1980s. The architecturally notable St. George's Greek Orthodox Cathedral, founded in 1907 and built in 1940, reflects Memorial Square's past as a Greek enclave.

A portion of the neighborhood was listed on the National Register of Historic Places in 1977 as the Memorial Square District.

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