Papageorgiou () is a Greek surname. It may refer to one of the following people:
Alexandra Papageorgiou (born 1980), Greek female athlete Christos Papageorgiou (disambiguation), several people Evangeline Papageorge (originally Papageorgiou) (1906–2001), American biochemist George Papageorgiou (born c.1958), Greek-American football player and coach in the United States Kostas Papageorgiou (1945–2021), Greek poet and critic Kostas Papageorgiou, footballer born 1941. Konstantinos Papageorgiou, footballer born 1995. Michail Papageorgiou (1727–1796), Greek philosopher