Nell Gwyn (1650–1687) was an actress and long-time mistress of King Charles II of England.

Nell Gwyn may also refer to: Nell Gwyn (operetta), an 1884 work by Robert Planquette Nell Gwyn (1926 film), starring Dorothy Gish Nell Gwyn (1934 film), starring Anna Neagle Nell Gwynn (play), a 2015 play by Jessica Swale Nell Gwyn Stakes, a Group 3 flat horse race in Great Britain Nell Gwynne Tavern, a public house in Covent Garden, London Gargoyle Club, once the Nell Gwynne Revue, a strip club in Soho, London