M28, M-28, or M/28 may refer to:
Roads M-28 (Michigan highway), a state highway in Michigan M28 (Cape Town), a Metropolitan Route in Cape Town, South Africa M28 (Pretoria), a Metropolitan Route in Pretoria, South Africa
Military
United States M28/M-1928 Haversack, US Army haversack M28, a training rocket for the M270 Multiple Launch Rocket System where the warhead is replaced by a steel ballast and three smoke canisters.
Finland M28 Mosin–Nagant, a Finnish rifle
Italy Tromboncino M28 grenade launcher, an Italian weapon that attaches to a rifle
Aircraft Miles M.28 Mercury, a 1941 British aircraft PZL M28 Skytruck, a small Polish transport plane
Other Messier 28, a globular cluster in the constellation Sagittarius McLaren M28, a Formula One racing car A line of 28-volt power tools manufactured by Milwaukee Electric Tool Corporation