8I or 8-I can refer to:

Transportation MyAir (former IATA code: 8I), a 2004–2009 Italian low-cost airline Itapemirim Transportes Aéreos (2020–2022) (former IATA code: 8I), a former Brazilian airline 747-8i, a model of Boeing 747

Computing PowerXCell 8i, IBM model of Cell microprocessor ISO-8859-8-I, an IANA charset name

Other uses 8i (virtual reality), a New Zealand-based virtual reality company

See also SBB-CFF-FFS Ce 6/8 I I8 (disambiguation)