Palfreyman is a surname. Notable people with the surname include:
Brent Palfreyman (born 1945), Australian former first-class cricketer David Palfreyman (born 1966), English actor, musician, songwriter and poet
David Palfreyman (born 1945), Australian former Olympic Rower and rowing coach
George Palfreyman (1893–1936), American college football coach Nigel Palfreyman (born 1973), Australian rules footballer Stewart Palfreyman (born 1948), former Australian rules footballer Thomas Palfreyman (died c. 1589), English author and musician