HRHS may refer to: Hypoplastic right heart syndrome, a rare congenital heart defect
Schools Hampshire Regional High School, Westhampton, Massachusetts, United States Hickory Ridge High School, Harrisburg, North Carolina, United States Highlands Ranch High School, Highlands Ranch, Colorado, United States Holy Redeemer High School, Wilkes-Barre, Pennsylvania, United States Holy Rosary High School (New Orleans), Louisiana, United States Hood River Valley High School, Hood River, Oregon, United States Heritage Regional High School, Saint-Hubert, Quebec, Canada