GCO may refer to:
Gemini Air Cargo, a defunct American cargo airline Genesco, an American footwear retailer GeorgiaCarry.org, an American gun rights organization Gotham Chamber Opera, a defunct American opera company Graphics and Calligraphy Office, a unit of the Social Office at the White House Grande ceinture Ouest, a section of the Grande Ceinture de Paris Ground communication outlet, a system installed at some U.S. airports