Francis Lewis (1713–1802) was a signer of the United States Declaration of Independence as a representative of New York.
Francis Lewis may also refer to:
Francis Lewis (botanist) (1875–1955), English botanist Francis Lewis High School, New York Francis Lewis (MP) (c. 1692–1744), English politician Francis Lewis (Trinidad and Tobago politician) Francis Draper Lewis (1849–1930), Philadelphian lawyer, co-founded the law firm Morgan, Lewis, later Morgan, Lewis & Bockius SS Francis Lewis on List of Liberty ships
See also Frances Moloney née Lewis, Irish socialite and nun
Frank Lewis (disambiguation)