Pupovac () is a Serbian surname, derived from the noun pup (bud). The surname refers to the wealthy medieval clan spreading out into a few family branches in the territory of Zadar County. It may refer to:

Adrijana Pupovac, Serbian politician Branka Pupovac, Australian wheelchair tennis player Milorad Pupovac, Croatian-Serb politician and linguist Sergio Pupovac, Luxembourg footballer

See also