John Lyttelton may refer to:
John Lyttelton, 9th Viscount Cobham (1881–1949), British politician John Lyttelton (MP) (1561–1601), English politician John Lyttelton, 11th Viscount Cobham (1943–2006), British nobleman Sir John Lyttelton (1520–1590) (1519–1590), constable of Dudley Castle, England, keeper of parks, Custos Rotulorum of Worcestershire
John Littleton Using an alternative spelling: John Littleton (born 1957), an American artist John Littleton (sheriff), High Sheriff of Cornwall
See also John Littleton Dawson (1813–1870), Democratic member of the U.S. House of Representatives from Pennsylvania