Palfrey is an occupational surname, denoting a person responsible for the maintenance and provision of saddle horses. Notable people with the surname include:
Daf Palfrey (born 1973), Welsh television, film and video director, producer and writer Deborah Jeane Palfrey (1956–2008), operated an escort agency in Washington, D.C., convicted in 2008 of racketeering, money laundering, etc. Francis Winthrop Palfrey (1831–1889), American historian, born in Boston, Massachusetts son of J. G. Palfrey John G. Palfrey (1796–1881), American clergyman and historian who served as a U.S. Representative from Massachusetts John Palfrey (born 1972), faculty co-director of the Berkman Center for Internet & Society at Harvard Law School Judith Palfrey (born 1943), the T. Berry Brazelton Professor of Pediatrics at Harvard Medical School Lisa Palfrey, Welsh television actress best known for playing the character of Rhiannedd Frost in the Welsh soap Pobol y Cwm Mianne Palfrey, American tennis player Polly Palfrey Woodrow (1906–1997), American tennis player Quentin Palfrey (born 1974), American lawyer Sarah Palfrey Cooke (1912–1996), female tennis player from the United States Sean Palfrey (born 1968), Welsh professional darts player who currently plays in the Professional Darts Corporation Simon Palfrey, English Scholar at Oxford University and a Fellow in English at Brasenose College, Oxford University Stephen Palfrey Webb (1804–1879), 3rd & 12th Mayor of Salem, Massachusetts (1842–1845, 1860–1862) and 6th Mayor of San Francisco (1854–1855) Thomas Palfrey (born 1953), currently (as of 2007) the Flintridge Professor of Economics and Political Science at the California Institute of Technology William Palfrey (1741–1780), American Patriot born in Boston, Massachusetts Yolande Palfrey (1957–2011), British actress
See also Mr. Palfrey of Westminster, British television drama which ran in 1984–85 Mrs. Palfrey at the Claremont, 2005 comedy-drama film made by Claremont Films