Darby House or The Darby House or variations may refer to:

in England Darby Houses, in Coalbrookdale, a museum in Shropshire

in the United States (by state then town) E. H. Darby Lustron House, Florence, Alabama, a Lustron house that is listed on the National Register of Historic Places (NRHP) in Lauderdale County The Darby House (Dawson Springs, Kentucky), listed on the NRHP in Hopkins County Darby House (Baldwin, Louisiana), listed on the NRHP in St. Mary Parish Darby House, of Darby Plantation (New Iberia, Louisiana), listed on the NRHP in Iberia Parish Darby House, of Darby Store historic site, in Beallsville, Maryland Darby House, the main house of Darby Dan Farm, in Galloway, Ohio Darby Meeting, also known as Darby Friends Meeting House, in Darby, Pennsylvania, NRHP-listed Darby House, of Darby Plantation (Edgefield, South Carolina), listed on the NRHP in Edgefield County

See also Darby Plantation (disambiguation)