William S. Burroughs (1914–1997) was an American writer and visual artist and beat generation personality.

William Burroughs may also refer to: William Seward Burroughs I (1857–1898), American inventor, grandfather of the writer William S. Burroughs Jr. (1947–1981), American novelist, son of the writer Sir William Burroughs, 1st Baronet (c. 1753–1829), Attorney General of Bengal and MP for Enniskillen, Colchester and Taunton

See also William Burrows (disambiguation) William Burrough (disambiguation)