Lois Wilson may refer to:
Lois W. also known as Lois Wilson (née Burnham) (1891–1988), American co-founder of Al-Anon and wife of Alcoholics Anonymous founder Bill W. Lois Wilson (actress) (1894–1988), actress in silent films Lois Miriam Wilson (1927–2024), first female Moderator of the United Church of Canada, 1980–1982 Lois Wilson (Doctors), a fictional character from the British soap opera Doctors Lois Wilson Langhorst (née Lois Wilson; 1914–1989), American modernist architect