John Appleton (1815–1864) was an American Assistant Secretary of State and Democratic Party politician from Maine.
John Appleton is also the name of:
John Appleton (academic), Master of University College, Oxford, England (c. 1401–8) John E. C. Appleton (1905–1990), Australian theatre and radio producer John F. Appleton (1838–1870), American Civil War general from Maine John James Appleton (1792–1864), diplomat for the United States John Appleton (judge) (1804–1891), Justice of the Maine Supreme Judicial Court John Howard Appleton (1844–1930), American chemist
See also Jon Appleton (1939–2022), American composer, author and professor of music
Appleton (disambiguation)