Jamaica Chamber of Commerce Building is a historic office building located in the Jamaica section of the New York City borough of Queens. It was designed in 1928 by George W. Conable (1866-1933) and is a ten-story, T-shaped building in the Colonial Revival style.

George W. Conable designed the building's facade based on 19th-century American and British precedents. It is a steel-frame building faced in red brick and trimmed in stone and terra cotta detail. It has tripartite massing with a one-story terra cotta base, six story section, and stepped back eighth and ninth stories. The top story is a one-story pedimented temple. ()

It was listed on the National Register of Historic Places in 1983.

See also List of New York City Designated Landmarks in Queens National Register of Historic Places listings in Queens County, New York

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