Lesina may refer to:
Places and jurisdictions Croatia Hvar, an island in Split–Dalmatia County, also known as Lesina in Italian and English Hvar (city), the largest city on the island
Italy Lesina, Apulia, a comune in the Province of Foggia Roman Catholic Diocese of Lesina, now a Latin titular see Lake Lesina, a lake in the Province of Foggia, Apulia Foggia Airfield Complex, a military airfield in the Province of Foggia of which Lesina airfield was a part
Other Lesina (katydid), an insect genus in the family Tettigoniidae