Jacquot (, ) is a French surname. Notable people with the surname include:

Benoît Jacquot (born 1947), French film director Charles Jean-Baptiste Jacquot (1812–1880), French writer better known by his pen name Eugène de Mirecourt Georges Jacquot (1794–1874), French sculptor of the 19th century Joe Jacquot, Deputy Attorney General of the state of Florida, USA Martine L. Jacquot (born 1955), French-born Canadian academic, novelist, poet, short story writer, journalist Rene Jacquot (born 1961), French professional boxer and world title holder

See also Jacot