Mrs. John Jacob Astor may refer to:
Sarah Todd Astor (1762–1842), wife of John Jacob Astor Charlotte Augusta Gibbes Astor (1825–1887), wife of John Jacob Astor III Madeleine Talmage Force (1893–1940), wife of John Jacob Astor IV Violet Astor, Baroness Astor of Hever (1889–1965), wife of John Jacob Astor, 1st Baron Astor of Hever One of several women married to John Jacob Astor VI