Asatiani () is a Georgian surname that may refer to:
Kakhi Asatiani (1947–2002), Soviet footballer and manager Lado Asatiani (1917–1943), Soviet poet Maia Asatiani (born 1977), Georgian TV host Malkhaz Asatiani (born 1981), Georgian footballer Mikheil Asatiani (1882–1938), Georgian psychiatrist Nugzar Asatiani (1937–1992), Soviet fencer Tina Asatiani (1918–2011), Armenian physicist