Lakes Region or Lake Region may refer to:

Regions African Great Lakes region Finger Lakes Region, New York, United States Great Lakes region, North America Lakes Region (New Hampshire), United States Los Lagos Region, Chile Turkish Lakes Region, Anatolia, Turkey Uwharrie Lakes Region, North Carolina, United States Willandra Lakes Region, New South Wales, Australia

Education Lake Region High School (disambiguation), multiple high schools Lake Region State College, a two-year public college in Devils Lake, North Dakota, United States Lake Region Union High School, a high school in Barton, Vermont, United States Lakes Region Community College, Laconia, New Hampshire, United States

Other uses Lakes Region Facility, a former state prison in Laconia, New Hampshire, United States Lakes Region League, an athletics league in New Hampshire Lakes Region News Club, a private newspaper publishing company in New Hampshire