William Aspinwall (1605–c. 1662) was a resident of the Massachusetts Bay Colony.
William Aspinwall may also refer to:
William Aspinwall (minister) (fl. 1648–1662), nonconformist English minister William Aspinwall (physician) (1743–1823), American physician William Henry Aspinwall (1807–1875), American railroad businessman
See also William Aspinall (disambiguation)