Smitherman is a surname. Notable people with the surname include:
A. J. Smitherman (1883-1961), American journalist George Smitherman (born 1964), Canadian politician Carole Smitherman (born 1952), American politician, served as City Councilor and Mayor of Birmingham, Alabama Rodger Smitherman, American politician, Democratic member of the Alabama Senate Christopher Smitherman, American politician, Cincinnati City Council Stephen Smitherman (born 1978), American Major League Baseball left fielder Joseph T. Smitherman (1929–2005), American politician, Mayor of Selma, Alabama from 1964 to 2000 Joseph T. Smitherman Historic Building, a historical building in Selma