William Ayloffe may refer to:
William Ayloffe (judge) (c. 1535–1584), English judge of the Queen's Bench and father of the 1st Baronet Sir William Ayloffe, 1st Baronet (1563–1627), of the Ayloffe baronets, MP for Stockbridge Sir William Ayloffe, 3rd Baronet (1618–1675), of the Ayloffe baronets, Royalist army officer
See also Ayloffe (surname)