Khortytsia is a large island on the Dnieper River in Ukraine.

Khortytsia may also refer to: Khortytsia Castle, a castle reportedly built on "Little Khortytsia Island" in the 1550s by Dmytro Vyshnevetsky ("Baida") Khortytsia, Zaporizhzhia Raion, a village in Zaporizhzhia Oblast Khortytsia Raion, a district of the city of Zaporizhzhia Khortytsia (company), a Ukrainian company that produces alcoholic beverages, in particular horilkas Chortitza Colony, a Russian Mennonite community located at Khortytsia Island

See also Mennonite settlements in Canada: Chortitz, Manitoba, in the Rural Municipality of Stanley Randolph, Manitoba, formerly known as Chortitz, in the Rural Municipality of Hanover Chortitz, Saskatchewan, in Rural Municipality of Coulee No. 136 Chortitzer Mennonite Conference, a group of Mennonite churches in western Canada Chortitz Heritage Church