Amusan is a surname. Notable people with the surname include:
Adewale Sunday Amusan (born 1989), Nigerian footballer Bolaji Amusan (born 1966), Nigerian comic actor Olusola Amusan (born 1990), Nigerian social entrepreneur Oluwole Olayiwola Amusan, Nigerian academic Tobi Amusan (born 1997), Nigerian sprinter and hurdler