Thomas Willis (1621–1675) was an English physician and anatomist.
Thomas Willis may also refer to:
Thomas Willis (Clerk of the Crown in Chancery) (1576–1656), high-ranking official during the English Civil War Thomas H. Willis (1850–1925), American painter Tom Willis (soccer) (born 1983), Australian goalkeeper Tom Willis (rugby union, born 1979), New Zealand rugby union player Tom Willis (rugby union, born 1999), England rugby union player Thomas Willis (sailor) (1756–1797), sailor with the second voyage of James Cook Tom Willis (politician), member of the West Virginia Senate Tom Willis (The Jeffersons), character in the American sitcom The Jeffersons
See also Thomas Willys, MP Thomas Wills (disambiguation)