Grubel or Grübel is a surname. Notable people with the surname include:
Herb Grubel (born 1934), Canadian politician Markus Grübel (born 1959), German politician Melchior Grübel, (1500–1561), Swiss soldier and merchant Oswald Grübel (born 1943), German businessman
Other Grubel–Lloyd index, measures intra-industry trade