Sprague is a surname, and may refer to:

A Abner E. Sprague (1850–1943), American pioneer in Colorado Achsa W. Sprague (1827–1862), American spiritualist Amasa Sprague (1798–1843), American businessman and politician from Rhode Island Amasa Sprague Jr. (1828–1902), American businessman and politician from Rhode Island Andrew Sprague (born 2005), American football player Augustus B. R. Sprague (Augustus Brown Reed Sprague, 1827–1910), American businessman, politician and military figure from Massachusetts Benona Sprague (1833–1908), United States Army corporal awarded the Medal of Honor

B Billy Sprague (born 1952), American Christian musician Bud Sprague (1904–1973), American football player Burr Sprague (1836-1917), American lawyer and politician

C Carl T. Sprague (1895-1979), American country musician Chandler Sprague (died 1955), American veteran, screenwriter and journalist Charles Sprague (poet) (1791–1875), American poet Charles A. Sprague (1887–1969), Governor of Oregon, 1939–1943 Charles F. Sprague (1857–1902), American politician from Massachusetts Charles Ezra Sprague (1842–1912), American accountant Charles James Sprague (1823–1903), American botanist Charlie Sprague (1864–1912), American baseball player Clifton Sprague (1896–1955), American admiral during World War II

D Dale Sprague, American politician David Sprague (1910–1968), Canadian football player David Sprague (rower) (born 1952), British rower Dick Sprague (1931–2008), American football player

E E. Carleton Sprague (Eben Carleton Sprague 1822–1895), American lawyer and politician from New York Ed Sprague Sr. (1945–2020), American baseball pitcher Ed Sprague Jr. (born 1967), American baseball player Edward Sprague or Edward Spragge (c.1620–1673), Irish admiral of the Royal Navy Edward H. Sprague (1848–1930), American politician from Wisconsin Elmer Sprague (1924–2019), American philosopher and academic Eric Sprague (1894–1947), Australian rules footballer Erik Sprague (born 1972), American freak show and sideshow performer Ernest Sprague (1865–1938), American football player, public official and engineer Ernest L. Sprague (1876–1944), American politician from Rhode Island Ezra T. Sprague (1833–1888), American lawyer, politician and judge from Wisconsin

F Farah Sprague (1891–1967), Persian-American writer, lecturer and hostess Frank J. Sprague (1857–1934), American naval officer, inventor and electrical engineer Frank Lee Sprague (1958–2018), American guitarist and composer Franklin B. Sprague (1825–1895), American military officer, businessman and judge Frederick Sprague (1794–1865), American farmer and politician from Wisconsin

G George Sprague (1871–1963), American businessman and mayor of Dallas George F. Sprague (1902–1998), American geneticist George R. Sprague (1938–2016), American politician from Massachusetts

H Henry H. Sprague (1841–1920), American lawyer and politician from Massachusetts Homer Sprague (1829–1918), American military officer, author and educator

I Ian Sprague (1920–1994), Australian studio potter Isaac Sprague (1811–1895), American botanical illustrator Isaac W. Sprague (1841–1887), American sideshow performer

J J. Russell Sprague (1886–1969), American politician Jack Sprague (born 1964), American racing driver Jake Sprague (born 1984), American rugby union footballer and coach Jo Ann Sprague (born 1931), American politician from Massachusetts John Sprague (doctor) (1718–1797), American physician John Allison Sprague (1844–1907), Canadian farmer and politician from Ontario J. Russell Sprague (John Russell Sprague, 1886–1969), American lawyer and politician from New York State John T. Sprague (1810–1878), United States Army officer John W. Sprague (1817–1894), American soldier and railroad executive Joseph Sprague (1783–1854), American businessman and politician from Brooklyn

K Ken Sprague (born 1945), American bodybuilder, businessman and schoolteacher Ken Sprague (cartoonist) (1927–2004), English political cartoonist Kent Sprague, American singer, drummer and composer Kristen Babb-Sprague (born 1968), American synchronized swimmer

L Leigh Sprague (born 1970), American attorney Lucian Sprague (1882–1960), American railroad executive Lucy J. Sprague (1851–1903), American suffragist Lucy Sprague, married name Lucy Sprague Mitchell (1878–1967), American educator, writer and college dean

M Mansfield D. Sprague (1910–2006), American politician from Connecticut Martyn Sprague (born 1949), Welsh footballer Marshall Sprague (1909–1994), American journalist and author M. Estella Sprague (1870–1940), American home economist and academic administrator

N Nathan B. Sprague (1787–1864), American farmer and politician from Rhode Island Nathan Turner Sprague (1828–1903), American businessman, banker and politician from Vermont

O Oliver M. W. Sprague (1873–1953), American economist

P Peleg Sprague (Maine politician) (1793–1880), American politician and judge Peleg Sprague (New Hampshire politician) (1756–1800), American politician Peter Sprague (born 1955), American jazz musician

R Reg Sprague (1886–1972), New Zealand rugby league footballer Richard E. Sprague (1921–1996), American computer technician and Kennedy assassination researcher Robert Sprague (born 1973), American politician from Ohio Robert Sprague (racing driver) (born 1959), American stock car driver Robert C. Sprague (1900–1991), American inventor and founder of Sprague Electric Roderick Sprague (1933–2012), American anthropologist and archeologist R. B. Sprague (1937–2010), American artist Roger Sprague (1769–1848), American businessman and politician in New York and the Territory of Michigan Roland Sprague (1894–1967), German mathematician Royal Sprague (1814–1872), American judge in California

S Samuel Sprague (1753–1844), American Revolutionary War officer, father of Charles Sprague the poet Stuart Sprague, American nephrologist Sydney Sprague (born 1992), American singer-songwriter and multi-instrumentalist

T Thomas Archibald Sprague (1877–1958), Scottish botanist Thomas Bond Sprague (1830–1920), British actuary Thomas L. Sprague (1894–1972), American vice admiral in World War II

V Viette Brown Sprague (1846–1923), American missionary in China

W William Sprague (1609–1675), American settler William Sprague III (1799–1856), American industrialist and politician from Rhode Island William Sprague IV (1830–1915), American politician from Rhode Island, nephew of William Sprague III William Sprague (Michigan politician) (1809–1868), American politician William Buell Sprague (1795–1876), American minister and author W. G. R. Sprague (William George Robert Sprague 1863–1933), London theatre designer William P. Sprague (1827–1899), American politician from Ohio

See also Spragg Spragge