Rothermel is a surname. Notable people with the surname include:
Bobby Rothermel (1870–1927), American infielder in Major League Baseball in 1899 John Hoover Rothermel (1856–1922), Democratic member of the U.S. House of Representatives from Pennsylvania P. Frederick Rothermel (1850–1929), Pennsylvania lawyer and politician Peter F. Rothermel (1817–1895), American painter