Tylee is a surname. Notable people with the surname include:

André Tylee, English psychiatrist Arthur Kellam Tylee, Canadian officer James Tylee, American politician Marion Tylee, New Zealand artist

Given name Tylee Craft (2001–2024), American football player Tylee Ryan, a victim in a 2019 murder case

See also Ty Lee, a character in the television series Avatar: The Last Airbender Tylee Cottage Residency, an artist-in-residence programme in Whanganui, New Zealand