Lacalle is a surname. Notable people with the surname include:
Alfi Conteh-Lacalle (born 1985), Spanish–Sierra Leonean footballer Andrés García La Calle (1909–1980), squadron leader of the 1st fighter squadron of the Spanish Republic and later Commander of all the fighter units of the Spanish Republican Air Force Borja Lacalle (born 2001), Spanish field hockey player Daniel Lacalle (born 1967), Spanish economist Fernando Sáenz Lacalle (born 1932), the tenth Bishop and sixth Archbishop of San Salvador, El Salvador Javier Lacalle (born 1969, Spanish politician Javier Zurbano Lacalle (born 1980), Spanish former footballer Joseph LaCalle (1860–1937), clarinettist, composer, conductor and music critic Luis Alberto Lacalle (born 1941), Uruguayan lawyer and politician who served as President of Uruguay from 1990 to 1995 Luis Alberto Lacalle Pou (born 1973), Uruguayan lawyer and politician, current President of Uruguay since March 2020
See also La Calle (disambiguation) López de Lacalle