Thomas Best may refer to:
Politicians Thomas Best (MP for Canterbury) (c. 1713–1795), MP for Canterbury Thomas Best (MP for Lewes) (fl. 1446/7), MP for Lewes Thomas Best (MP for Ripon) (1589–c. 1649), MP for Ripon
Others Thomas Best (navy captain) (1570?–1638?), English naval captain Thomas Best (basketball), played in 1980–81 NCAA Division I men's basketball season Thomas Best (writer), author of 1787 English book A Concise Treatise on the Art of Angling Tommy Best (1920–2018), Welsh footballer
See also Thomas Best Woodward (1814–1875), Protestant chaplain in the County Gaol, Downpatrick and Dean of Down Thomas Alexander Vans Best, British colonial administrator