Peperomia columella is a species of plant in the family of Piperaceae. The species is endemic to Peru. It grows in dry areas, often in crevices on steep cliffs or in sandy soil.Christensen-Dean, Gay A.; Moore, Randy; Development of Chlorenchyma and Window Tissues in Leaves of Peperomia columella. Annals of Botany 71:141-146 1993

It grows to about 20 cm in height, forming snake-like stems, which carry closely packed, succulent bright green leaves. The leaves are truncated, U-shape in cross-section, with epidermal windows on top.

It can be kept as a houseplant and has received the Award of Garden Merit by the Royal Horticultural Society.

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