Diona may refer to:
People with the given name Diona Doherty (born 1989), Irish actress Diona Reasonover (born 1992), American actress
Places Diona, Mali, a village and the seat of Korarou, Mali Diona, Illinois, an unincorporated community in Coles County, Illinois, United States
Fictional characters Diona, a character in 2020 video game Genshin Impact