Samedov (, ) is an Azerbaijani surname. Notable people with the surname include:
Aleksandr Samedov (born 1984), Russian footballer Alihan Samedov (born 1964), Soviet and Azerbaijani musician Thrill Pill, stage name of Timur Tofikovich Samedov (born 2000), Russian rapper Zabit Samedov (born 1984), Azerbaijani kickboxer