The Women's 4 × 100 metres relay at the 2010 Commonwealth Games as part of the athletics programme was held at the Jawaharlal Nehru Stadium on Tuesday 12 October 2010.

Records World Record 41.37 Canberra, Australia 6 October 1985 Games Record 42.44 Manchester, England 2002

Final Rank Lane Nation Competitors Time Notes 4Katherine Endacott, Montell Douglas, Laura Turner, Abiodun Oyepitan 44.19 8Rosina Amenebede, Elizabeth Amolofo, Beatrice Gyaman, Janet Amponsah 45.24 2Sathi Geetha, Srabani Nanda, P. K. Priya, Hiriyur Jyothi 45.254 7Seun Adigun, Comfort Onyali, Josephine Ehigie, Agnes Osazuwa 48.87 – 6Andrea Bliss, Shanna Thomas, Audria Segree, Dominique Blake DSQ – 3Mahriam Kamara, Rebecca Ansumana, Leticia Macauley, Michaela Kargbo DSQ – 5 DNS

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