Mr & Mrs may refer to:

Mr and Mrs (game show), a United Kingdom television show Mr. and Mrs. (2012 film), a film starring Nse Ikpe Etim and Joseph Benjamin "Mister and Missus", series 7 episode 8 of Where the Heart Is English honorifics, among others including Miss, Ms, Sir, Dr, Lady or Lord Mr., for men Mrs., for women Mr & Mrs (1992 film), directed by Sajan Mr. & Mrs. a comic strip created 1919 by Clare Briggs for the New York Herald Tribune. The last creator was Kin Platt until 1963.

See also All Star Mr & Mrs, a British television show Mr. & Mrs. '55, a 1955 Indian romantic comedy film Marriage, a union between spouses Mr & Miss, a 2021 Indian romantic drama film by T. Ashok Kumar Reddy Mr. & Mrs. Smith (disambiguation)