This is a chronological list of spaceflights to the International Space Station (ISS), including long-term ISS crew, short term visitors, replacement/rescue missions and mixed human/cargo missions. Uncrewed visiting spacecraft are excluded (see Uncrewed spaceflights to the International Space Station for details). ISS crew members are listed in bold. "Time docked" refers to the spacecraft and does not always correspond to the crew.

, 290 people from 26 countries had visited the space station, many of them multiple times. The United States sent 170 people, Russia sent 64, 11 were Japanese, nine were Canadian, six were Italian, four were French, four were German, two from the United Arab Emirates, Hungary and Saudi Arabia and one each from Belgium, Brazil, Denmark, Israel, Kazakhstan, Malaysia, the Netherlands, India, Turkey, Belarus, South Africa, Poland, South Korea, Spain, Sweden, and the United Kingdom.

U.S. Space Shuttle missions were capable of carrying more humans and cargo than the Russian Soyuz spacecraft, resulting in more U.S. short-term human visits until the Space Shuttle program was discontinued in 2011. Between 2011 and 2020, Soyuz was the sole means of human transport to the ISS, delivering mostly long-term crew. Russian cargo deliveries have been exclusively carried out by the uncrewed missions of Progress spacecraft, requiring fewer human spaceflights.

U.S. return to flight to the ISS began in March 2019 after SpaceX's Crew Dragon completed its uncrewed Demo-1 mission before completing its piloted Demo-2 in May 2020.

Continued international collaboration on ISS missions has been thrown into doubt by the 2022 Russian invasion of Ukraine and related sanctions on Russia, but is still continuing as of 2026.

The ISS is set to be decommissioned and deorbited in 2030, however, in 2025 Russia announced its intention to "recycle" the Russian Orbital Segment as the basis for their new Russian Orbital Station. The first segment of the private U.S. Axiom Station, the Payload Power Thermal Module, is also set to attach to the ISS before the second module, Habitat One, is launched.

Completed

ISS flight Mission Crew Crew photo Notes 1. 2A STS-88EndeavourLaunch:December 4, 1998Time docked:6 days 18h Robert D. Cabana Frederick W. Sturckow Nancy J. Currie Jerry L. Ross James H. Newman Sergei Krikalev Deliver Unity Module 3 spacewalks 2. 2A.1 STS-96DiscoveryLaunch:May 27, 1999Time docked:5 days 18h Kent V. Rominger Rick D. Husband Tamara E. Jernigan Ellen L. Ochoa Daniel T. Barry Julie Payette Valeri Tokarev 1 spacewalk 3. 2A.2a STS-101 AtlantisLaunch:May 19, 2000Time docked:5 days 18h James D. Halsell Scott J. Horowitz Mary E. Weber Jeffrey N. Williams James S. Voss Susan J. Helms Yury Usachev Boost orbit ~30 km 1 spacewalk 4. 2A.2b STS-106AtlantisLaunch:September 8, 2000Time docked:7 days 21h Terrence W. Wilcutt Scott D. Altman Edward T. Lu Richard A. Mastracchio Daniel C. Burbank Yuri Malenchenko Boris Morukov 1 spacewalk 5. 3A STS-92DiscoveryLaunch:October 11, 2000Time docked:6 days 21h Brian Duffy Pamela A. Melroy Leroy Chiao William S. McArthur Peter J. K. Wisoff Michael E. Lopez-Alegria Koichi Wakata Deliver Z1 Truss 4 spacewalks 6. 2R Soyuz TM-31Launch:October 31, 2000Time docked:~183 days Yuri Gidzenko Sergei Krikalev William M. Shepherd Deliver Expedition 1 crew, the first long-duration stay. 7. 4A STS-97EndeavourLaunch:November 30, 2000Time docked:6 days 23h Brent W. Jett Michael J. Bloomfield Joseph R. Tanner Carlos I. Noriega Marc Garneau Deliver P6 Truss 3 spacewalks 8. 5A STS-98AtlantisLaunch:February 7, 2001Time docked:6 days 21h Kenneth D. Cockrell Mark L. Polansky Robert L. Curbeam Marsha S. Ivins Thomas D. Jones Deliver Destiny Laboratory 3 spacewalks 9. 5A.1 STS-102DiscoveryLaunch:March 8, 2001Time docked:8 days 21h James D. Wetherbee James M. Kelly Paul W. Richards Andrew S. W. Thomas Yury Usachev James S. Voss Susan J. Helms Deliver Expedition 2 crew Return Expedition 1 crew Use MPLM 2 spacewalks 10. 6A STS-100EndeavourLaunch:April 19, 2001Time docked:8 days 3h Kent V. Rominger Jeffrey S. Ashby John L. Phillips Scott E. Parazynski Chris A. Hadfield Umberto Guidoni Yuri Lonchakov Use MPLM Deliver Canadarm2 2 spacewalks 11. 2S Soyuz TM-32Launch:April 28, 2001Time docked:~183 days Talgat Musabayev Yuri Baturin Dennis A. Tito All three crew returned on Soyuz TM-31 after a week 12. 7A STS-104 AtlantisLaunch:July 12, 2001Time docked:8 days 1h Steven W. Lindsey Charles O. Hobaugh Michael L. Gernhardt Janet L. Kavandi James F. Reilly Deliver Quest Joint Airlock 3 spacewalks 13. 7A.1 STS-105 DiscoveryLaunch:August 10, 2001Time docked:9 days 20h Scott J. Horowitz Frederick W. Sturckow Daniel T. Barry Patrick G. Forrester Frank L. Culbertson Mikhail Tyurin Vladimir Dezhurov Deliver Expedition 3 crew Return Expedition 2 crew Use MPLM 2 spacewalks 14. 3S Soyuz TM-33Launch:October 21, 2001Time docked:~193 days Viktor Afanasyev Konstantin Kozeyev Claudie Haigneré All three crew members returned on Soyuz TM-32 after 9 days 18 hours. 15. UF-1 STS-108 EndeavourLaunch:December 5, 2001Time docked:7 days 21h Dominic L. Pudwill Gorie Mark E. Kelly Linda M. Godwin Daniel M. Tani Yuri Onufrienko Carl E. Walz Daniel W. Bursch Deliver Expedition 4 crew Return Expedition 3 crew Use MPLM 1 spacewalk 16. 8A STS-110 AtlantisLaunch:April 8, 2002Time docked:7 days 2h Michael J. Bloomfield Stephen N. Frick Jerry L. Ross Steven L. Smith Ellen L. Ochoa Lee M. E. Morin Rex J. Walheim Deliver S0 Truss 4 spacewalks 17. 4S Soyuz TM-34Launch:April 25, 2002Time docked:~196 days Yuri Gidzenko Roberto Vittori Mark Shuttleworth All three crew returned on Soyuz TM-33 after 8 days 18. UF-2 STS-111 EndeavourLaunch:June 5, 2002Time docked:7 days 22h Kenneth D. Cockrell Paul S. Lockhart Franklin R. Chang-Diaz Philippe Perrin Valery Korzun Sergei Treshchev Peggy A. Whitson Deliver Expedition 5 crew Return Expedition 4 crew Deliver Mobile Base System Use MPLM 3 spacewalks 19. 9A STS-112 AtlantisLaunch:October 7, 2002Time docked:6 days 21h Jeffrey S. Ashby Pamela A. Melroy David A. Wolf Sandra H. Magnus Piers J. Sellers Fyodor Yurchikhin Deliver S1 Truss 3 spacewalks 20. 5S Soyuz TMA-1Launch:October 30, 2002Time docked:~183 days Sergei Zalyotin Yuri Lonchakov Frank De Winne All three crew returned on Soyuz TM-34 after a week 21. 11A STS-113 EndeavourLaunch:November 24, 2002Time docked:6 days 22h James D. Wetherbee Paul S. Lockhart Michael E. Lopez-Alegria John B. Herrington Kenneth D. Bowersox Donald R. Pettit Nikolai Budarin Deliver Expedition 6 crew Return Expedition 5 crew Deliver P1 Truss 3 spacewalks Note: The Space Shuttle Columbia disaster occurred on February 1, 2003, grounding the Space Shuttle fleet until July 2005. Major ISS construction was suspended and resumed in September 2006 with STS-115. 22. 6S Soyuz TMA-2Launch:April 28, 2003Time docked:~182 days Yuri Malenchenko Edward T. Lu Deliver Expedition 7 crew in Soyuz TMA-1 a few days later 23. 7S Soyuz TMA-3Launch:October 18, 2003Time docked:~192 days Alexander Kaleri Michael Foale Pedro Duque Deliver Expedition 8 crew Duque returned with the Expedition 7 crew on Soyuz TMA-2 a few days later 24. 8S Soyuz TMA-4Launch:April 19, 2004Time docked:~185 days Gennady Padalka Michael Fincke André Kuipers Deliver Expedition 9 crew Kuipers returned with the Expedition 8 crew on Soyuz TMA-3 9 days later 25. 9S Soyuz TMA-5Launch:October 14, 2004Time docked:~190 days Salizhan Sharipov Leroy Chiao Yuri Shargin Deliver Expedition 10 crew Shargin returned with the Expedition 9 crew on Soyuz TMA-4 a few days later 26. 10S Soyuz TMA-6Launch:April 15, 2005Time docked:~179 days Sergei Krikalev John L. Phillips Roberto Vittori Deliver Expedition 11 crew Vittori returned with the Expedition 10 crew on Soyuz TMA-5 a few days later 27. LF1 STS-114DiscoveryLaunch:July 26, 2005Time docked:8 days 20h Eileen M. Collins James M. Kelly Stephen K. Robinson Andrew S. W. Thomas Wendy B. Lawrence Charles J. Camarda Soichi Noguchi Return to flight mission Use MPLM Space Shuttle inspection from ISS 3 spacewalks 28. 11S Soyuz TMA-7Launch:October 1, 2005Time docked:~189 days Valery Tokarev William S. McArthur Gregory H. Olsen Deliver Expedition 12 crew Olsen returned with the Expedition 11 crew on Soyuz TMA-6 a few days later 29. 12S Soyuz TMA-8Launch:March 30, 2006Time docked:~180 days Pavel Vinogradov Jeffrey N. Williams Marcos Pontes Deliver Expedition 13 crew Pontes returned with the Expedition 12 crew on Soyuz TMA-7 9 days later 30. ULF1.1 STS-121DiscoveryLaunch:July 4, 2006Time docked:8 days 19h Steven W. Lindsey Mark E. Kelly Michael E. Fossum Lisa M. Nowak Stephanie D. Wilson Piers J. Sellers Thomas Reiter Deliver Reiter for Expedition 13 crew Space Shuttle inspection from ISS 3 spacewalks 31. 12A STS-115AtlantisLaunch:September 9, 2006Time docked:6 days 2h Brent W. Jett Christopher J. Ferguson Daniel C. Burbank

Joseph R. Tanner Steven G. MacLean Deliver P3/4 truss Space Shuttle inspection from ISS 3 spacewalks 32. 13S Soyuz TMA-9Launch:Time docked:~215 days Mikhail Tyurin Michael E. Lopez-Alegria / Anousheh Ansari Deliver Expedition 14 crew Ansari returned with the Expedition 13 crew on Soyuz TMA-8 8 days later 33. 12A.1 STS-116DiscoveryLaunch:December 10, 2006Time docked:7 days 23h Mark L. Polansky William A. Oefelein Nicholas J. M. Patrick Robert L. Curbeam Joan E. Higginbotham Christer Fuglesang Sunita L. Williams Deliver Williams for Expedition 14 crew Deliver P5 truss Space Shuttle inspection from ISS 4 spacewalks 34. 14S Soyuz TMA-10Launch:April 7, 2007Time docked:~196 days Oleg Kotov Fyodor Yurchikhin / Charles Simonyi Deliver Expedition 15 crew Simonyi returned with the Expedition 14 crew on Soyuz TMA-9 12 days later 35. 13A STS-117AtlantisLaunch:June 8, 2007Time docked:8 days 19h Frederick W. Sturckow Lee J. Archambault Patrick G. Forrester Steven R. Swanson John D. Olivas James F. Reilly Clayton C. AndersonDeliver Anderson for Expedition 15 crew Deliver S3/4 truss Space Shuttle inspection from ISS 4 spacewalks 36. 13A.1 STS-118EndeavourLaunch:August 8, 2007Time docked:8 days 18h Scott J. Kelly Charles O. Hobaugh Tracy E. Caldwell Dyson Richard A. Mastracchio Barbara R. Morgan Benjamin A. Drew Dafydd R. WilliamsDeliver S5 Truss Space Shuttle inspection from ISS 4 spacewalks 37. 15S Soyuz TMA-11Launch:October 10, 2007Time docked:~189 days Yuri Malenchenko Peggy A. Whitson Sheikh Muszaphar ShukorDeliver Expedition 16 crew Shukor returned with the Expedition 15 crew on Soyuz TMA-10 a few days later 38. 10A STS-120DiscoveryLaunch:October 23, 2007Time docked:10 days 22h Pamela A. Melroy George D. Zamka Scott E. Parazynski Stephanie D. Wilson Douglas H. Wheelock Paolo Nespoli Daniel M. TaniDeliver Tani for Expedition 16 crew Deliver Harmony Module Relocate P6 truss Space Shuttle inspection from ISS 5 spacewalks 39. 1E STS-122AtlantisLaunch:February 7, 2008Time docked:8 days 16h Stephen N. Frick Alan G. Poindexter Leland D. Melvin Rex J. Walheim Stanley G. Love Hans Schlegel Léopold EyhartsDeliver Eyharts for Expedition 16 crew Deliver Columbus module Space Shuttle inspection from ISS 3 spacewalks 40. 1J/A STS-123EndeavourLaunch:March 11, 2008Time docked:11 days 21h Dominic L. Pudwill Gorie Gregory H. Johnson Robert L. Behnken Michael J. Foreman Richard M. Linnehan Takao Doi Garrett E. ReismanDeliver Reisman for Expedition 16 crew Deliver Kibō Experiment Logistics Module and Special Purpose Dexterous Manipulator Space Shuttle inspection from ISS 5 spacewalks 41. 16S Soyuz TMA-12Launch:April 8, 2008Time docked:~198 days Sergei Volkov Oleg Kononenko Yi So YeonDeliver Expedition 17 crew Yi returned with the Expedition 16 crew on Soyuz TMA-11 a few days later 42. 1J STS-124DiscoveryLaunch:May 31, 2008Time docked:8 days 17h Mark E. Kelly Kenneth T. Ham Karen L. Nyberg Ronald J. Garan