This is a list of Live with Regis and Kelly episodes which were broadcast during the show's 22nd season. The list is ordered by air date.

Although the co-hosts may have read a couple of emails during the broadcast, it does not necessarily count as a "Regis and Kelly Inbox" segment.

denotes that a particular segment WAS aired. denotes that a particular segment WAS NOT aired. denotes a "Special Week" (usually a week in which the show is taken on location) denotes a "Special Episode" denotes a "Theme Week"

September 2009 Date Co-Hosts "Host Chat" Retrieved November 25, 2009 Guests/Segments Retrieved November 25, 2009 "Regis and Kelly Inbox" Retrieved November 25, 2009 September 7 Regis Philbin & Kelly Ripa Stephen Moyer, Jerry Ferrara, and Rachel Zoe September 8 Regis Philbin & Kelly Ripa Queen Latifah and AnnaLynne McCord September 9 Regis Philbin & Kelly Ripa Tyler Perry and Michael Douglas September 10 Regis Philbin & Kelly Ripa Jason Bateman, Amber Tamblyn, and Smokey Robinson September 14 Regis Philbin & Kelly Ripa Chace Crawford, Michael Strahan, Kim Clijsters, and Guinness World Record Breaker Week September 15 Regis Philbin & Kelly Ripa Aaron Eckhart, Laura Leighton, and Guinness World Record Breaker Week September 16 Regis Philbin & Kelly Ripa Megan Fox, Serena Williams, and Guinness World Record Breaker Week September 17 Regis Philbin & Kelly Ripa Dennis Quaid, 2009 NASCAR Sprint Cup Series, and Guinness World Record Breaker Week September 18 Kelly Ripa & David Duchovny America's Got Talent winner Kevin Skinner, Ricky Gervais, and Guinness World Record Breaker Week September 21 Regis Philbin & Kelly Ripa Julianna Margulies and David Gray September 22 Regis Philbin & Kelly Ripa Christian Slater and LL Cool J September 23 Regis Philbin & Kelly Ripa Clive Owen and Melina Kanakaredes September 24 Regis Philbin & Kelly Ripa Laurence Fishburne and Whitney Port September 25 Kelly Ripa & Jeff Probst Jude Law, John Krasinski, and Jo Frost September 28 Regis Philbin & Kelly Ripa Eli Manning and 2009 Relly Awards September 29 Regis Philbin & Kelly Ripa Patricia Heaton and 2009 Relly Awards September 30 Regis Philbin & Kelly Ripa Kelsey Grammer and 2009 Relly Awards

October 2009 Date Co-Hosts "Host Chat" Guests/Segments "Regis and Kelly Inbox" October 1 Regis Philbin & Kelly Ripa Woody Harrelson and 2009 Relly Awards October 2 Kelly Ripa & Mark Consuelos Selena Gomez, Disney Familyfun's 18th Annual Toy of the Years Awards, and 2009 Relly Awards October 5 Regis Philbin & Kelly Ripa Eddie Cibrian and Melissa Etheridge October 6 Regis Philbin & Kelly Ripa Larry David and John Stamos October 7 Regis Philbin & Kelly Ripa Chevy Chase and Julie Andrews October 8 Regis Philbin & Kelly Ripa Vince Vaughn and Michael Kors October 9 Kelly Ripa & Anderson Cooper Padma Lakshmi and Joss Stone October 12 Regis Philbin & Kelly Ripa Forest Whitaker and Alicia Keys October 13 Regis Philbin & Kelly Ripa Uma Thurman and Ivanka Trump October 14 Regis Philbin & Kelly Ripa Minnie Driver, Colbie Caillat, and Regis gets a flu shot October 15 Regis Philbin & Kelly Ripa Mario Lopez and Monty Python October 16 Kelly Ripa & Anderson Cooper Penn Badgley and Halloween Masks October 19 Regis Philbin & Kelly Ripa Hilary Swank, Memory Expert Dave Farrow, and CFA Iams Cat Championship October 20 Regis Philbin & Kelly Ripa Garry Shandling and Jane Krakowski October 21 Regis Philbin & Kelly Ripa Ewan McGregor and Jim Cramer October 22 Regis Philbin & Kelly Ripa Willem Dafoe and Tracy Morgan October 23 Kelly Ripa & Kyle MacLachlan Jason Alexander and Eugene Levy October 26 Regis Philbin & Kelly Ripa Judge Judy and Halloween Week October 27 Regis Philbin & Kelly Ripa Courteney Cox, Creed, and Halloween Week October 28 Regis Philbin & Kelly Ripa Patrick Dempsey, Brody Jenner, and Halloween Week October 29 Regis Philbin & Kelly Ripa Daniel Craig, Don Rickles, and Halloween Week October 30 Regis Philbin & Kelly Ripa LIVE's Reality Bites Halloween Spectacular, Donald Trump, and Carrie Ann Inaba

November 2009 Date Co-Hosts "Host Chat" Guests/Segments "Regis and Kelly Inbox" November 2 Regis Philbin & Kelly Ripa Jenny McCarthy and Ted Danson November 3 Regis Philbin & Kelly Ripa Reba McEntire and Emeril Lagasse November 4 Regis Philbin & Kelly Ripa Julia Louis-Dreyfus and Sean Kingston November 5 Regis Philbin & Kelly Ripa Bernadette Peters and Carrie Underwood November 6 Regis Philbin & Kelly Ripa James Marsden and Project Runway Finalists November 9 Regis Philbin & Kelly Ripa Meredith Vieira, Dana Delany, and Home for the Holiday Makeovers Week November 10 Regis Philbin & Kelly Ripa John Cusack, Robin Roberts, and Home for the Holiday Makeovers Week November 11 Regis Philbin & Kelly Ripa Andre Agassi, Martin Short, and Home for the Holiday Makeovers Week November 12 Regis Philbin & Kelly Ripa Kate Walsh and Home for the Holiday Makeovers Week November 13 Regis Philbin & Kelly Ripa Jimmy Smits, Jamie Oliver, and Home for the Holiday Makeovers Week November 16 Regis Philbin & Kelly Ripa Anderson Cooper and The Hayes Family November 17 Regis Philbin & Kelly Ripa Keanu Reeves and Heidi & Spencer Pratt November 18 Regis Philbin & Kelly Ripa Kristen Stewart and Kris Allen November 19 Regis Philbin & Kelly Ripa Robert Pattinson, America's Next Top Model Winner, and Thanksgiving Food with Joy November 20 Regis Philbin & Kelly Ripa Penélope Cruz, Taylor Lautner, and Kelly & Mark go back to "All My Children" November 23 Regis Philbin & Kelly Ripa LIVE! in Las Vegas, Mark Harmon, David Cook, Project Runway winner Irina Shabayeva makes Kelly a wedding dress and Kelly learns some of the acrobatic moves that make the unbelievable show La Rêve such a sensational attraction November 24 Regis Philbin & Kelly Ripa LIVE! in Las Vegas, Jimmy Kimmel, Carrot Top and Kelly relives her trip down the aisle at the popular "Chapel of the Bells" November 25 Regis Philbin & Kelly Ripa LIVE! in Las Vegas, Thomas Gibson, Regis & Joy and Kelly visits the cast of "The Beatles Love" by Cirque du Soleil November 27 Regis Philbin & Kelly Ripa LIVE! in Las Vegas, Thanksgiving Leftovers, Neil Patrick Harris, Uncle Kracker and Regis takes a special helicopter ride above the Vegas strip and stops at the breathtaking Grand Canyon November 30 Regis Philbin & Kelly Ripa Matt Dillon, Ashley Greene, Miranda Cosgrove, and Pete Yorn and Scarlett Johansson

December 2009 Date Co-Hosts "Host Chat" Guests/Segments "Regis and Kelly Inbox" December 1 Kelly Ripa & Howie Mandel Cheryl Hines December 2 Kelly Ripa & Michael Bublé Morgan Freeman and Lance Armstrong December 3 Kelly Ripa & Anderson Cooper Meg Ryan, Jermaine, Tito, Jackie and Marlon Jackson December 4 Kelly Ripa & Christian Slater Kate Beckinsale and Sting December 7 Kelly Ripa & Bryant Gumbel Ray Romano, John Lithgow, and Inside The Chef's Kitchen December 8 Kelly Ripa & Bryant Gumbel Julianne Hough, Terrence Howard, and Inside The Chef's Kitchen December 9 Kelly Ripa & Jeff Probst Catherine Zeta-Jones, The Biggest Loser Winner, and Inside The Chef's Kitchen December 10 Kelly Ripa & Jeff Probst Mariah Carey, Billy Ray Cyrus, and Inside The Chef's Kitchen December 11 Kelly Ripa & Jeff Probst Kate Hudson, Kerry Washington, Inside The Chef's Kitchen December 14 Kelly Ripa & Anderson Cooper Colin Firth and Holiday Savings Gift Guide Week December 15 Kelly Ripa & Anderson Cooper Fergie, Ne-Yo, and Holiday Savings Gift Guide Week December 16 Kelly Ripa & Anderson Cooper Hugh Grant, Judi Dench, and Holiday Savings Gift Guide Week December 17 Kelly Ripa & Mark Consuelos Sarah Jessica Parker and Holiday Savings Gift Guide Week December 18 Kelly Ripa & Mark Consuelos Robert Downey, Jr. and Holiday Savings Gift Guide Week December 21 Kelly Ripa & Mark Consuelos Jude Law, Sting, Disney on Ice, Perfect Tree December 22 Kelly Ripa & Mark Consuelos LIVE's Holiday Celebration, Nicole Kidman, David Archuleta, The Rockettes and Tavern on the Green

January 2010 Date Co-Hosts "Host Chat" Guests/Segments "Regis and Kelly Inbox" January 4 Regis Philbin & Kelly Ripa Chris Meloni, Jake Pavelka, and New Year, New You: Guide to Better Eating Week January 5 Regis Philbin & Kelly Ripa Jenna Elfman, Chesley Sullenberger, and New Year, New You: Guide to Better Eating Week January 6 Regis Philbin & Kelly Ripa Tim Allen, Katharine McPhee, and New Year, New You: Guide to Better Eating Week January 7 Regis Philbin & Kelly Ripa Amy Adams, Gabourey Sidibe, and New Year, New You: Guide to Better Eating Week January 8 Kelly Ripa & Nick Jonas Zach Braff, Marion Cotillard, and New Year, New You: Guide to Better Eating Week January 11 Regis Philbin & Kelly Ripa Valerie Bertinelli and Nathan Fillion January 12 Regis Philbin & Kelly Ripa Jennifer Connelly January 13 Regis Philbin & Kelly Ripa Freddie Prinze, Jr. and Tim Gunn January 14 Regis Philbin & Kelly Ripa Kiefer Sutherland and Norah Jones January 15 Kelly Ripa & Mark Consuelos Denzel Washington, Matt Bomer, and Fitness Friday January 18 Regis Philbin & Kelly Ripa Jeff Bridges, Ian Somerhalder, Carrie Underwood and Peter Gros January 19 Regis Philbin & Kelly Ripa Randy Jackson and Ashley Judd January 20 Regis Philbin & Kelly Ripa Dwayne Johnson and Becki Newton January 21 Regis Philbin & Kelly Ripa Brendan Fraser, Masi Oka, and Richard "Ack Ack" Ackerman January 22 Kelly Ripa & Jerry O'Connell Harrison Ford, Lucy Lawless, and Fitness Friday January 25 Kelly Ripa & Mark Consuelos Glenn Close and Tracey Ullman January 26 Kelly Ripa & Martin Short Josh Duhamel and Home Remedies January 27 Kelly Ripa & David Duchovny Claire Danes January 28 Kelly Ripa & Jeff Probst Julianne Moore and Nick Thompson January 29 Kelly Ripa & Mark Consuelos Kristen Bell, Christine Baranski, Project Ack Ack, and Fitness Friday

February 2010 Date Co-Hosts "Host Chat" Guests/Segments "Regis and Kelly Inbox" February 1 Regis Philbin & Kelly Ripa Jonathan Rhys Meyers February 2 Regis Philbin & Kelly Ripa Jesse Tyler Ferguson and Vanessa Williams February 3 Regis Philbin & Kelly Ripa Jessica Alba and Channing Tatum February 4 Regis Philbin & Kelly Ripa Michael Strahan, John Travolta, and Project Ack Ack February 5 Regis Philbin & Kelly Ripa Robin Thicke, Pierce Brosnan, Project Ack Ack, and Fitness Friday February 8 Regis Philbin & Kelly Ripa Bill Paxton, Project Ack Ack, and Inside the Chef's Kitchen - Chocolate Challenge February 9 Regis Philbin & Kelly Ripa Rosario Dawson, Project Ack Ack, and Inside the Chef's Kitchen - Chocolate Challenge February 10 Regis Philbin & Kelly Ripa Jennifer Garner, Ruby Gettinger, Project Ack Ack and Inside the Chef's Kitchen - Chocolate Challenge February 11 Regis Philbin & Kelly Ripa Kim Kardashian and Inside the Chef's Kitchen - Chocolate Challenge February 12 Regis Philbin & Kelly Ripa Jessica Biel, Inside the Chef's Kitchen - Chocolate Challenge, and Fitness Friday February 15 Regis Philbin & Kelly Ripa Reggie Bush, Taye Diggs, Corbin Bleu, Project Ack Ack, and Regis & Kelly's Crash Course February 16 Regis Philbin & Kelly Ripa Nicole Richie, Regis & Kelly's Crash Course, and Daytona 500 Winner February 17 Regis Philbin & Kelly Ripa Lauren Fix, Michelle Williams, Christoph Waltz, and Regis & Kelly's Crash Course February 18 Regis Philbin & Kelly Ripa Sir Ben Kingsley, Shenae Grimes, and Regis & Kelly's Crash Course February 19 Regis Philbin & Kelly Ripa Ewan McGregor, Regis & Kelly's Crash Course, and Fitness Friday February 22 Regis Philbin & Kelly Ripa Ethan Hawke, Shaun White, and Coast to Coast Makeovers February 23 Regis Philbin & Kelly Ripa Diane Sawyer and Coast to Coast Makeovers February 24 Regis Philbin & Kelly Ripa Jeffrey Donovan, Joan Rivers, and Coast to Coast Makeovers February 25 Regis Philbin & Kelly Ripa Bruce Willis and Coast to Coast Makeovers February 26 Regis Philbin & Kelly Ripa Maggie Gyllenhaal, Coast to Coast Makeovers, and Fitness Friday

March 2010