Persis is a feminine given name, meaning "from Persia". Notable people with the name include:
Persis Drell (born 1955), American physicist Persis Karim (born 1962), American poet, editor, educator Persis Khambatta (1948–1998), Indian actress and model Persis Kirmse (1884–1955), British painter Persis Goodale Thurston Taylor (1821–1906), Hawaiian artist Persis Robertson (1896–1992), American artist