Makepeace is an English surname derived from the medieval English Mak(en), to make, plus Pais, peace. It originally designated a mediator, one who is skilled at negotiation of hostilities. It may refer to:

People Brian Makepeace (born 1931), English footballer Chris Makepeace (born 1964), Canadian film and television actor Harry Makepeace (1881–1952), English cricketer and footballer John Makepeace (born 1939), British furniture designer and maker Jonathan Makepeace (1774–1850), American businessman and politician Mary Lou Makepeace, American activist and politician, first female mayor of Colorado Springs (1997–2003) Ralph Makepeace (1909–1995), English footballer Reginald Makepeace (1890–1918), British First World War flying ace Troy Makepeace (born 1979), Australian rules footballer William Makepeace Thackeray (1811–1863), British novelist, author and illustrator

Fictional characters Detective Sergeant Lady Harriet "Harry" Makepeace, in Dempsey and Makepeace, a British television crime drama Quentin Makepeace, a villain in the Bartimaeus Sequence series of children's novels Colonel Makepeace, in Stargate SG-1 Tom Makepeace, in House of Cards Winter Makepeace and Asa Makepeace, in the Maiden Lane series of romance novels by Elizabeth Hoyt Abel Makepeace, in MacGyver Corrine Calloway, née Makepeace, protagonist in Brightness Falls, The Good Life (novel), and Bright, Precious Days, a trilogy of novels by Jay McInerney

See also C. R. Makepeace & Company, a defunct architectural firm in Rhode Island, United States D. E. Makepeace Company, a historical building in Attleboro, Massachusetts, United States George Makepeace House, a historical building in Madison, Indiana, United States