MPU or Mpu may refer to:

Science and technology Medical-grade polyurethane, a polyurethane used in medicine; for example see Vas-occlusive contraception

Computing Memory protection unit, for example in the ARM Cortex-M Microprocessor unit, a central processing unit when referring to digital signal processors MPU-401 (MIDI Processing Unit), an obsolete standard for MIDI interfaces for personal computers Multi-core processing unit, a system made of two or more independent cores; see History of general-purpose CPUs

Other uses Mabua Airstrip (IATA code: MPU), an airport in Papua New Guinea Melbourne Poets Union, a forerunner of Australian Poetry and later reincarnated under the same name Minimum publishable unit, the smallest piece of a scientist's results that can be made into an academic paper Myanmar Payment Union, a Myanmar financial services corporation Medical-psychological assessment in Germany, called MPU for Medizinisch-Psychologische Untersuchung Missing persons unit, a police unit to locate missing persons Missing Persons Unit, an Australian TV documentary series Alert: Missing Persons Unit, an American TV fiction series More Perfect Union (media organization) Mpu, a type of Kongo headwear Union Political Movement, a Moldovan political bloc named in Romanian