The Netherlands Football League Championship 1949–1950 was contested by 60 teams participating in six divisions. The national champion would be determined by a play-off featuring the winners of the eastern, northern, two southern and two western football divisions of the Netherlands. SV Limburgia won this year's championship by beating Blauw-Wit Amsterdam, Maurits, Ajax, sc Heerenveen and Enschedese Boys.
At the end of this season, the KNVB re-aligned the current system of Regional Divisions into 5 new Divisions for 1950–51, to be called Eerste Klasse A-E.
New entrants Eerste Klasse South-I: Moving in from South-II: SC Helmondia, SV Kerkrade, NOAD, PSV Eindhoven and Sittardse Boys Promoted from 2nd Division: RBC Roosendaal Eerste Klasse South-II: Moving in from South-I: BVV Den Bosch, Juliana, NAC, VV TSC and Willem II Eerste Klasse West-I: Moving in from West-II: Feijenoord, Hermes DVS, KFC, VSV and Zeeburgia Eerste Klasse Wëst-II: Moving in from West-I: AFC Ajax, HVV 't Gooi, SVV, De Volewijckers and Xerxes Promoted from 2nd Division: RCH
Divisions
Eerste Klasse East
Eerste Klasse North
Eerste Klasse South-I
Eerste Klasse South-II
Eerste Klasse West-I
Eerste Klasse West-II
Championship play-off
References RSSSF Netherlands Football League Championships 1898-1954 RSSSF Eerste Klasse Oost RSSSF Eerste Klasse Noord RSSSF Eerste Klasse Zuid RSSSF Eerste Klasse West